CEP104

Across TCGA patient cohorts, CEP104 mutation is significantly associated with the RNA expression of many other genes, with 2,820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP104-associated genes across cancer lineages are UGDH, ICMT, and MESD. Each is linked with CEP104 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP104-to-partner and partner-to-CEP104 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGDH grouped by CEP104-low versus CEP104-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP104→partner) and Y-score (partner→CEP104) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UGDH →	+0.733	+3.209	.001	.009	3	3
COAD	ICMT →	+0.449	+3.210	.002	.009	3	3
COAD	MESD →	+0.486	+3.375	.001	.005	3	3
COAD	DBR1 →	+0.443	+3.240	.001	.008	3	3
COAD	YARS2 →	+0.437	+3.348	.005	.005	3	3
COAD	ELAC1 →	+0.612	+3.389	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,820 associations by consensus.

UGDH by CEP104 expression — COAD

Explore this box plot interactively →