CEP104

Across TCGA cell cohorts, CEP104 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,509 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEP104-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Positive regulation of autophagy of mitochondrion. Each is linked with CEP104 in more than 15 cancer types. Because this analysis shows association rather than direction, both CEP104-to-partner and partner-to-CEP104 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by CEP104-low versus CEP104-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP104→partner) and Y-score (partner→CEP104) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.127	+0.644	.001	.001	3	16
OESOPHAGUS	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.169	+0.895	.001	<.001	3	16
BONE	Positive regulation of autophagy of mitochondrion →	+0.099	+0.833	.001	.001	3	16
STOMACH	Response to methionine →	+0.122	+0.940	<.001	.005	3	16
STOMACH	Cellular response to methionine →	+0.122	+0.940	<.001	.005	3	16
KIDNEY	Regulation of autophagy of mitochondrion →	+0.100	+1.228	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,509 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by CEP104 expression — BONE

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