CEP104

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CEP104 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEP104-associated genes across cancer lineages are IFNG, HRG, and CNTN6. Each is linked with CEP104 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP104-to-partner and partner-to-CEP104 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNG grouped by CEP104-low versus CEP104-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP104→partner) and Y-score (partner→CEP104) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaIFNG →+0.268+4.567<.001.00131
BLOOD_LeukemiaHRG →+0.351+3.855<.001.00731
BLOOD_LeukemiaCNTN6 →+0.216+3.855<.001.00731
BLOOD_LeukemiaKAAG1 →+0.097+3.855<.001.00731
BLOOD_LeukemiaFATE1 →+0.108+3.551<.001.00931
BLOOD_LeukemiaSPATA19 →+0.018+4.984<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

IFNG by CEP104 expression — BLOOD_Leukemia

Box plot of IFNG in CEP104-low vs CEP104-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration