CENPX

Across TCGA patient cohorts, CENPX RNA expression is significantly associated with the protein abundance of many other proteins, with 16,435 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPX-associated proteins across cancer lineages are PAF1, RRM2, and MCM2. Each is linked with CENPX in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPX-to-partner and partner-to-CENPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPX versus PAF1 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPX→partner) and Y-score (partner→CENPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PAF1 →	+0.238	+0.590	<.001	<.001	3	7
LUAD	RRM2 →	+0.815	+0.756	<.001	<.001	3	7
GBM	MCM2 →	+0.629	+0.327	<.001	<.001	3	7
LUAD	MCM2_S139 →	+0.841	+0.552	<.001	<.001	3	7
LSCC	MCM4 →	+0.666	+0.589	<.001	<.001	3	7
GBM	MCM5 →	+0.650	+0.317	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,435 associations by consensus.

CENPX vs PAF1 — LSCC

Explore this scatter interactively →