CENPX

Across TCGA patient cohorts, CENPX protein abundance is significantly associated with the RNA expression of many other genes, with 8,470 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPX-associated genes across cancer lineages are OIP5, FOXM1, and CDCA3. Each is linked with CENPX in more than 3 cancer types. Because this analysis shows association rather than direction, both CENPX-to-partner and partner-to-CENPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPX versus OIP5 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPX→partner) and Y-score (partner→CENPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	OIP5 →	+0.851	+0.900	.001	<.001	3	4
BRCA	FOXM1 →	+1.599	+0.928	<.001	<.001	3	4
BRCA	CDCA3 →	+1.388	+0.896	<.001	<.001	3	4
LSCC	TTK →	+1.364	+0.910	<.001	<.001	3	4
LSCC	ECT2 →	+1.235	+1.119	.001	<.001	3	4
BRCA	CENPA →	+1.513	+0.778	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,470 associations by consensus.

CENPX vs OIP5 — LSCC

Explore this scatter interactively →