Across TCGA pan-cancer cohorts, CENPVL3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CENPVL3’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CENPVL3 RNA is repressed in tumor relative to normal tissue. In most cancer types CENPVL3 is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.

BRCA, KIRC, and PRAD are the cancer types where CENPVL3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CENPVL3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.037	<.001	4	view →
KIRC	All	All	−0.015	.013	4	view →
PRAD	All	All	+0.310	<.001	2	view →
LUSC	All	All	+0.120	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CENPVL3 RNA expression & survival · all CENPVL3 data types