CENPV

Across TCGA patient cohorts, CENPV protein abundance is significantly associated with the RNA expression of many other genes, with 15,605 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPV-associated genes across cancer lineages are ROBO2, ZNF850, and DOK3. Each is linked with CENPV in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPV-to-partner and partner-to-CENPV results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPV versus ROBO2 in GBM, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPV→partner) and Y-score (partner→CENPV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ROBO2 →	+1.211	+0.609	<.001	.009	3	7
OV	ZNF850 →	+0.921	+0.625	<.001	<.001	3	7
LSCC	DOK3 →	-0.532	-0.484	.001	.005	3	6
BRCA	ZFYVE9 →	+0.540	+0.750	<.001	<.001	3	6
HNSC	C1orf115 →	+1.102	+0.665	<.001	<.001	3	6
GBM	ZNF704 →	+1.158	+0.714	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,605 associations by consensus.

CENPV vs ROBO2 — GBM

Explore this scatter interactively →