CENPV

Across TCGA patient cohorts, CENPV mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CENPV-associated genes across cancer lineages are HERC2P7, CYP4F36P, and RN7SKP104. Each is linked with CENPV in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPV-to-partner and partner-to-CENPV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HERC2P7 grouped by CENPV-low versus CENPV-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPV→partner) and Y-score (partner→CENPV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HERC2P7 →	+0.083	+3.329	.002	.004	3	1
UCEC	CYP4F36P →	+0.527	+3.520	<.001	.002	3	1
UCEC	RN7SKP104 →	+0.085	+4.727	<.001	.003	3	1
UCEC	RNU6-770P →	+0.331	+3.430	.005	.007	3	1
UCEC	RNU6-280P →	+0.307	+4.923	<.001	.002	3	1
UCEC	RNU6-879P →	+0.767	+3.903	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

HERC2P7 by CENPV expression — UCEC

Explore this box plot interactively →