CENPUP1

Across TCGA pan-cancer cohorts, CENPUP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CENPUP1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where CENPUP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CENPUP1 is over-expressed in tumor.

UCEC, STAD, and LUSC are the cancer types where CENPUP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CENPUP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.125	.037	2	view →
STAD	Female	All	+0.038	.031	2	view →
LUSC	All	All	+0.006	.030	2	view →
BRCA	All	II,III,IV	+0.004	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CENPUP1–UCEC

Open the UCEC breakdown →