CENPQ

Across TCGA patient cohorts, CENPQ protein abundance is significantly associated with the RNA expression of many other genes, with 11,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPQ-associated genes across cancer lineages are PLK1, CDKN3, and GINS1. Each is linked with CENPQ in more than 5 cancer types. Because this analysis shows association rather than direction, both CENPQ-to-partner and partner-to-CENPQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPQ versus PLK1 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPQ→partner) and Y-score (partner→CENPQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLK1 →	+1.267	+0.556	<.001	.007	3	6
OV	CDKN3 →	+1.174	+0.535	<.001	<.001	3	5
UCEC	GINS1 →	+1.387	+0.780	<.001	<.001	3	5
GBM	E2F1 →	+1.738	+1.370	<.001	<.001	3	5
GBM	FAM83D →	+1.795	+1.390	<.001	<.001	3	5
GBM	CENPI →	+1.681	+1.560	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,938 associations by consensus.

CENPQ vs PLK1 — UCEC

Explore this scatter interactively →