Across TCGA pan-cancer cohorts, CENPP Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CENPP data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CENPP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CENPP expression acts as an unfavorable survival marker.

LUAD and PRAD are the cancer types where CENPP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.036	0.682	<.001	12	view →
PRAD	DFS	Median	All	0.617	0.886	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CENPP tumor-vs-normal RNA expression · all CENPP data types