Across TCGA cell cohorts, CENPP RNA expression is significantly associated with the RNA expression of many other genes, with 9,813 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPP-associated genes across cancer lineages are SMC2, POLE3, and RMI1. Each is linked with CENPP in more than 18 cancer types. Because this analysis shows association rather than direction, both CENPP-to-partner and partner-to-CENPP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPP→partner) and Y-score (partner→CENPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SMC2 →	+1.761	+1.522	<.001	<.001	3	19
BLOOD_Myeloma	POLE3 →	+1.298	+1.490	<.001	<.001	3	18
LIVER	RMI1 →	+1.126	+1.011	<.001	.002	3	18
OESOPHAGUS	NCBP1 →	+1.036	+1.466	<.001	.002	1	19
UPPER_AERODIGESTIVE_TRACT	FANCC →	+1.125	+1.640	<.001	<.001	3	16
BLOOD_Myeloma	CLSPN →	+1.788	+1.309	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,813 associations by consensus.

Exploration

CENPP survival (RNA) · tumor vs normal (RNA) · all CENPP data types