CENPO

Across TCGA pan-cancer cohorts, CENPO mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CENPO data layer compared with 28 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher CENPO mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CENPO expression acts as an unfavorable survival marker.

GBM, CCRCC, and HNSC are the cancer types where CENPO mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.289	0.696	.026	5	view →
CCRCC	DFS	Quartile	All	0.712	1.000	.032	2	view →
HNSC	OS	Median	III,IV	0.937	1.000	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CENPO–GBM (DFS)

Open the GBM breakdown →