CENPO

Across TCGA patient cohorts, CENPO protein abundance is significantly associated with the RNA expression of many other genes, with 7,514 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPO-associated genes across cancer lineages are TGIF1, LINC02605, and CEP76. Each is linked with CENPO in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPO-to-partner and partner-to-CENPO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPO versus TGIF1 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPO→partner) and Y-score (partner→CENPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TGIF1 →	+0.611	+0.509	<.001	.004	3	3
LSCC	LINC02605 →	-0.960	-0.674	<.001	<.001	3	3
OV	CEP76 →	+0.494	+0.329	.003	.001	3	2
OV	ACVR1C →	+0.784	+0.279	.004	.006	3	2
LSCC	BBS10 →	+0.520	+0.457	<.001	<.001	3	2
LSCC	UBA7 →	-0.790	-0.620	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,514 associations by consensus.

CENPO vs TGIF1 — HNSC

Explore this scatter interactively →