CENPO

Across TCGA patient cohorts, CENPO mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CENPO-associated genes across cancer lineages are DC, Astrocytes, and pDC. Each is linked with CENPO in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPO-to-partner and partner-to-CENPO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DC grouped by CENPO-low versus CENPO-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPO→partner) and Y-score (partner→CENPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DC →	+0.025	+3.326	.018	.009	3	3
BLCA	Astrocytes →	+0.088	+2.556	.018	.026	3	1
UCEC	pDC →	+0.071	+2.815	.005	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DC by CENPO expression — UCEC

Explore this box plot interactively →