CENPO

Across TCGA cell cohorts, CENPO RNA expression is significantly associated with the go_rna of many other GO terms, with 5,172 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPO-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Mitotic nuclear division, and Regulation of cell cycle checkpoint. Each is linked with CENPO in more than 19 cancer types. Because this analysis shows association rather than direction, both CENPO-to-partner and partner-to-CENPO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by CENPO-low versus CENPO-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPO→partner) and Y-score (partner→CENPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of cell cycle process →	+0.086	+1.576	<.001	<.001	3	20
OESOPHAGUS	Mitotic nuclear division →	+0.161	+1.491	<.001	<.001	3	20
OESOPHAGUS	Regulation of cell cycle checkpoint →	+0.165	+1.247	<.001	<.001	3	20
SOFT_TISSUE	Negative regulation of cell cycle phase transition →	+0.088	+1.533	<.001	<.001	3	20
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.122	+1.024	<.001	<.001	3	20
BREAST	Chromosome condensation →	+0.193	+1.227	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,172 associations by consensus.

Negative regulation of cell cycle process by CENPO expression — SOFT_TISSUE

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