Across TCGA pan-cancer cohorts, CENPNP2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CENPNP2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CENPNP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CENPNP2 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUSC and KIRC are the cancer types where CENPNP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CENPNP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.011	.022	2	view →
KIRC	All	II,III,IV	−0.007	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CENPNP2 RNA expression & survival · all CENPNP2 data types