CENPN-AS1

Across TCGA pan-cancer cohorts, CENPN-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CENPN-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CENPN-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CENPN-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and HNSC show a favorable association.

ACC, LGG, and MESO are the cancer types where CENPN-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.350	0.808	<.001	105	view →
LGG	DFS	Median	All	0.800	0.676	<.001	47	view →
MESO	DFS	Median	II,III,IV	0.264	0.636	.004	46	view →
HNSC	OS	Median	III,IV	0.488	0.214	.001	36	view →
CHOL	DFS	Median	IV	0.082	0.753	.008	21	view →
UCS	OS	Quartile	II,III,IV	0.568	0.254	.024	12	view →
THCA	OS	Quartile	All	0.789	1.000	.010	7	view →
KIRP	OS	Median	IV	0.045	0.523	.024	6	view →
BLCA	OS	Quartile	All	0.793	0.651	.021	6	view →
LAML	DFS	Median	All	0.251	0.539	.012	6	view →
KIRC	DFS	Tertile	III,IV	0.835	0.599	.011	4	view →
READ	OS	Tertile	All	0.860	0.506	.047	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CENPN-AS1–ACC (DFS)

Open the ACC breakdown →