CENPM

Across TCGA patient cohorts, CENPM protein abundance is significantly associated with the RNA expression of many other genes, with 15,070 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPM-associated genes across cancer lineages are GTSE1, MYBL2, and MCM4. Each is linked with CENPM in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPM-to-partner and partner-to-CENPM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPM versus GTSE1 in LUAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPM→partner) and Y-score (partner→CENPM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GTSE1 →	+1.657	+0.887	<.001	.002	3	7
LUAD	MYBL2 →	+2.915	+0.971	<.001	.001	3	6
LSCC	MCM4 →	+0.952	+0.584	<.001	<.001	3	6
LUAD	KIF18B →	+2.086	+0.660	<.001	.006	3	6
LUAD	SPAG5 →	+1.307	+0.818	.009	.005	3	6
UCEC	BIRC5 →	+1.664	+0.884	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,070 associations by consensus.

CENPM vs GTSE1 — LUAD

Explore this scatter interactively →