CENPL

Across TCGA patient cohorts, CENPL protein abundance is significantly associated with the RNA expression of many other genes, with 8,846 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPL-associated genes across cancer lineages are ASF1B, FOXM1, and NEK2. Each is linked with CENPL in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPL-to-partner and partner-to-CENPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPL versus ASF1B in HNSC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPL→partner) and Y-score (partner→CENPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ASF1B →	+1.240	+0.629	.002	.003	3	7
OV	FOXM1 →	+1.484	+0.525	<.001	.001	3	7
HNSC	NEK2 →	+1.367	+0.627	<.001	<.001	3	7
LUAD	KIF2C →	+1.469	+0.684	<.001	<.001	3	7
UCEC	CDCA5 →	+1.502	+0.753	<.001	<.001	3	7
OV	PLK1 →	+1.430	+0.725	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,846 associations by consensus.

CENPL vs ASF1B — HNSC

Explore this scatter interactively →