CENPK

Across TCGA patient cohorts, CENPK protein abundance is significantly associated with the RNA expression of many other genes, with 7,582 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CENPK-associated genes across cancer lineages are CDKN3, MCM4, and DLGAP5. Each is linked with CENPK in more than 5 cancer types. Because this analysis shows association rather than direction, both CENPK-to-partner and partner-to-CENPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPK versus CDKN3 in LUAD, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPK→partner) and Y-score (partner→CENPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDKN3 →	+1.144	+0.495	<.001	<.001	3	6
BRCA	MCM4 →	+1.226	+0.690	<.001	<.001	3	6
BRCA	DLGAP5 →	+1.596	+0.656	<.001	<.001	3	6
GBM	KIF23 →	+1.065	+0.664	<.001	.001	3	6
LUAD	KIF11 →	+1.308	+0.660	<.001	<.001	3	6
UCEC	CIP2A →	+1.149	+0.476	.004	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,582 associations by consensus.

CENPK vs CDKN3 — LUAD

Explore this scatter interactively →