CENPK

Across TCGA patient cohorts, CENPK mutation is significantly associated with the RNA expression of many other genes, with 182 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CENPK-associated genes across cancer lineages are LINC00708, OR13Z1P, and KRTAP19-5. Each is linked with CENPK in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPK-to-partner and partner-to-CENPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00708 grouped by CENPK-low versus CENPK-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPK→partner) and Y-score (partner→CENPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00708 →	+0.054	+4.984	<.001	.005	3	2
SKCM	OR13Z1P →	+0.091	+6.469	<.001	.001	3	2
BRCA	KRTAP19-5 →	+0.154	+5.540	.001	.004	3	2
BRCA	RNU7-106P →	+0.244	+7.471	<.001	.008	3	2
BRCA	RN7SL97P →	+0.172	+5.378	<.001	.006	3	2
BRCA	OR7E156P →	+0.876	+5.122	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

LINC00708 by CENPK expression — LUAD

Explore this box plot interactively →