CENPK

Across TCGA cell cohorts, CENPK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,965 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPK-associated GO terms across cancer lineages are Centriole replication, Double-strand break repair, and DNA recombination. Each is linked with CENPK in more than 19 cancer types. Because this analysis shows association rather than direction, both CENPK-to-partner and partner-to-CENPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole replication grouped by CENPK-low versus CENPK-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPK→partner) and Y-score (partner→CENPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Centriole replication →	+0.105	+1.189	.002	.003	3	20
SKIN	Double-strand break repair →	+0.071	+1.052	<.001	<.001	3	19
SKIN	DNA recombination →	+0.076	+1.001	<.001	<.001	3	19
SOFT_TISSUE	Immunoglobulin heavy chain V-D-J recombination →	+0.173	+0.800	<.001	<.001	3	19
BLOOD_Myeloma	Regulation of mitotic sister chromatid separation →	+0.149	+1.580	.001	.003	3	19
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle phase transition →	+0.074	+1.220	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,965 associations by consensus.

Centriole replication by CENPK expression — OESOPHAGUS

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