CENPJ

Across TCGA patient cohorts, CENPJ protein abundance is significantly associated with the RNA expression of many other genes, with 3,346 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPJ-associated genes across cancer lineages are PLK4, NKX2-1, and RPS2. Each is linked with CENPJ in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPJ-to-partner and partner-to-CENPJ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPJ versus PLK4 in GBM, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPJ→partner) and Y-score (partner→CENPJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLK4 →	+1.086	+0.707	.003	<.001	3	3
LUAD	NKX2-1 →	-1.605	-0.697	.004	.003	3	2
LUAD	RPS2 →	+0.510	+0.556	.002	<.001	3	2
GBM	LANCL3 →	-1.653	-0.745	.001	<.001	3	2
LUAD	MTSS1 →	-1.331	-0.658	<.001	<.001	3	2
LUAD	C1orf127 →	-0.971	-0.674	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,346 associations by consensus.

CENPJ vs PLK4 — GBM

Explore this scatter interactively →