CENPJ

Across TCGA cell cohorts, CENPJ RNA expression is significantly associated with the go_rna of many other GO terms, with 4,300 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CENPJ-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Replication fork processing, and Centrosome duplication. Each is linked with CENPJ in more than 19 cancer types. Because this analysis shows association rather than direction, both CENPJ-to-partner and partner-to-CENPJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by CENPJ-low versus CENPJ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPJ→partner) and Y-score (partner→CENPJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.105	+1.145	.004	.002	3	20
BONE	Replication fork processing →	+0.142	+1.450	.003	.001	3	20
BONE	Centrosome duplication →	+0.141	+1.309	.002	.004	3	19
BONE	Microtubule organizing center organization →	+0.099	+1.446	.001	.001	3	19
BONE	Centrosome cycle →	+0.102	+1.358	.002	.002	3	19
BONE	Centriole replication →	+0.143	+1.362	.003	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,300 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by CENPJ expression — BONE

Explore this box plot interactively →