CENPJ

Across TCGA cell cohorts, CENPJ mutation is significantly associated with the RNA expression of many other genes, with 148 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CENPJ-associated genes across cancer lineages are C16orf92, C12orf57, and SERPINA11. Each is linked with CENPJ in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPJ-to-partner and partner-to-CENPJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C16orf92 grouped by CENPJ-low versus CENPJ-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPJ→partner) and Y-score (partner→CENPJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	C16orf92 →	+0.134	+3.544	<.001	.002	3	2
BLOOD_Leukemia	C12orf57 →	+0.974	+3.489	.004	.001	3	2
BLOOD_Leukemia	SERPINA11 →	+0.007	+2.475	<.001	.007	3	2
LUNG_NSCLC_LUAD	NXNL1 →	+0.024	+5.228	.004	.005	3	1
LUNG_NSCLC_LUAD	OR2F2 →	+0.036	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR13C7 →	+0.049	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 148 associations by consensus.

C16orf92 by CENPJ expression — STOMACH

Explore this box plot interactively →