CENPH

Across TCGA patient cohorts, CENPH RNA expression is significantly associated with the protein abundance of many other proteins, with 24,141 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPH-associated proteins across cancer lineages are NPM1_S254, PAICS_S27, and CDK1. Each is linked with CENPH in more than 9 cancer types. Because this analysis shows association rather than direction, both CENPH-to-partner and partner-to-CENPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPH versus NPM1_S254 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPH→partner) and Y-score (partner→CENPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NPM1_S254 →	+1.093	+0.850	<.001	<.001	3	10
OV	PAICS_S27 →	+0.980	+0.788	<.001	<.001	3	10
LUAD	CDK1 →	+0.835	+0.744	<.001	<.001	3	10
UCEC	DHFR →	+0.607	+0.724	<.001	<.001	3	10
OV	FEN1 →	+0.750	+0.848	<.001	<.001	3	10
HNSC	GEMIN5 →	+0.276	+0.810	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,141 associations by consensus.

CENPH vs NPM1_S254 — LSCC

Explore this scatter interactively →