CENPH

Across TCGA patient cohorts, CENPH protein abundance is significantly associated with the RNA expression of many other genes, with 12,305 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPH-associated genes across cancer lineages are CCNB1, BRIP1, and KPNA2. Each is linked with CENPH in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPH-to-partner and partner-to-CENPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPH versus CCNB1 in LUAD, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPH→partner) and Y-score (partner→CENPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCNB1 →	+1.759	+0.549	<.001	<.001	3	7
LUAD	BRIP1 →	+1.607	+0.822	<.001	<.001	3	7
LUAD	KPNA2 →	+1.519	+0.784	<.001	<.001	3	7
LUAD	CDCA2 →	+1.960	+0.805	<.001	<.001	3	7
LUAD	DHFR →	+1.014	+0.651	<.001	.001	3	7
LUAD	RAD51 →	+1.112	+0.807	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,305 associations by consensus.

CENPH vs CCNB1 — LUAD

Explore this scatter interactively →