CENPF

Across TCGA patient cohorts, CENPF protein abundance is significantly associated with the RNA expression of many other genes, with 21,862 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPF-associated genes across cancer lineages are POLE2, CDKN3, and VRK1. Each is linked with CENPF in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPF-to-partner and partner-to-CENPF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPF versus POLE2 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPF→partner) and Y-score (partner→CENPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLE2 →	+0.867	+0.658	<.001	<.001	3	7
UCEC	CDKN3 →	+1.153	+0.686	<.001	<.001	3	7
HNSC	VRK1 →	+0.800	+0.358	<.001	<.001	3	7
UCEC	GINS1 →	+1.216	+0.777	<.001	<.001	3	7
BRCA	MYBL2 →	+1.610	+0.547	<.001	<.001	3	7
UCEC	E2F1 →	+1.195	+0.496	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,862 associations by consensus.

CENPF vs POLE2 — LSCC

Explore this scatter interactively →