CENPF

Across TCGA cell cohorts, CENPF mutation is significantly associated with the RNA expression of many other genes, with 903 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CENPF-associated genes across cancer lineages are SERPINA11, OR1L3, and DNAAF6. Each is linked with CENPF in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPF-to-partner and partner-to-CENPF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA11 grouped by CENPF-low versus CENPF-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPF→partner) and Y-score (partner→CENPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SERPINA11 →	+0.056	+3.635	<.001	.007	3	3
LUNG_NSCLC_LUAD	OR1L3 →	+0.009	+2.565	<.001	.002	3	3
BONE	DNAAF6 →	+0.030	+4.000	<.001	.008	3	2
KIDNEY	SSMEM1 →	+0.085	+3.947	.001	.003	3	2
LUNG_NSCLC_LUAD	CCDC174 →	-0.370	-3.265	<.001	.004	3	2
BLOOD_Leukemia	SENP3 →	+0.550	+3.489	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 903 associations by consensus.

SERPINA11 by CENPF expression — SOFT_TISSUE

Explore this box plot interactively →