CENPBD1

Across TCGA pan-cancer cohorts, CENPBD1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CENPBD1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CENPBD1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CENPBD1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

HNSC, THCA, and LIHC are the cancer types where CENPBD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CENPBD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.837	<.001	12	view →
THCA	Male	III,IV	−0.672	.001	9	view →
LIHC	Male	All	+0.577	<.001	5	view →
KIRC	All	II,III,IV	−0.348	.001	5	view →
CHOL	Male	All	+1.428	<.001	4	view →
STAD	Male	II,III,IV	+0.832	.002	4	view →
KIRP	All	II,III,IV	+0.463	.009	4	view →
KICH	All	All	−0.454	.007	4	view →
LUAD	All	All	+0.338	<.001	4	view →
LUSC	All	All	+0.341	.002	3	view →
ESCA	All	II,III,IV	+0.810	.045	2	view →
UCEC	All	All	−0.594	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CENPBD1–HNSC

Open the HNSC breakdown →