CENPA

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CENPA mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CENPA-associated genes across cancer lineages are Fibroblasts. Each is linked with CENPA in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPA-to-partner and partner-to-CENPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by CENPA-low versus CENPA-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPA→partner) and Y-score (partner→CENPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCFibroblasts →+0.054+5.339<.001.04731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Fibroblasts by CENPA expression — HNSC

Box plot of Fibroblasts in CENPA-low vs CENPA-high samples in HNSC.

Explore this box plot interactively →

Exploration