Across TCGA patient cohorts, CEND1 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEND1-associated genes across cancer lineages are SPDYE20P, RNVU1-28, and PPATP2. Each is linked with CEND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEND1-to-partner and partner-to-CEND1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEND1→partner) and Y-score (partner→CEND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPDYE20P →	+0.211	+3.722	.009	.002	3	1
UCEC	RNVU1-28 →	+0.726	+2.635	.004	.008	3	1
BLCA	PPATP2 →	+0.099	+7.640	<.001	.009	3	1
BLCA	PMS2P8 →	+0.074	+7.640	<.001	.009	3	1
UCEC	RN7SL147P →	+0.344	+4.620	<.001	<.001	3	1
UCEC	ADIG →	+0.244	+3.080	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

CEND1 survival (RNA) · tumor vs normal (RNA) · all CEND1 data types