CENATAC-DT

Across TCGA pan-cancer cohorts, CENATAC-DT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CENATAC-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CENATAC-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CENATAC-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.

KIRC, LIHC, and ACC are the cancer types where CENATAC-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.733	0.495	<.001	100	view →
LIHC	DFS	Median	All	0.470	0.611	<.001	51	view →
ACC	DFS	Median	All	0.568	0.880	.002	42	view →
UVM	OS	Quartile	All	0.821	0.382	.017	26	view →
READ	DFS	Tertile	All	0.845	0.241	.004	24	view →
BRCA	DFS	Quartile	IV	0.800	0.241	.003	23	view →
HNSC	DFS	Tertile	IV	0.743	0.557	.003	18	view →
KICH	DFS	Median	II,III,IV	0.697	0.959	.009	16	view →
LUSC	OS	Median	All	0.822	0.725	.005	15	view →
MESO	DFS	Median	IV	0.179	0.450	.013	12	view →
CHOL	DFS	Tertile	All	0.624	0.156	.018	12	view →
COAD	DFS	Quartile	II,III,IV	0.283	0.506	.021	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CENATAC-DT–KIRC (DFS)

Open the KIRC breakdown →