CEMIP2

Across TCGA patient cohorts, CEMIP2 mutation is significantly associated with the RNA expression of many other genes, with 4,356 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEMIP2-associated genes across cancer lineages are MDH1, PTGES2, and NTMT1. Each is linked with CEMIP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CEMIP2-to-partner and partner-to-CEMIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MDH1 grouped by CEMIP2-low versus CEMIP2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEMIP2→partner) and Y-score (partner→CEMIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MDH1 →	+0.524	+3.522	<.001	.002	3	4
LUAD	PTGES2 →	+0.435	+3.611	.003	.001	3	4
UCEC	NTMT1 →	+0.548	+1.722	<.001	<.001	3	4
LUAD	KMT5A →	+0.546	+3.468	<.001	.002	3	4
UCEC	ALAS1 →	+0.436	+2.736	<.001	<.001	3	4
LUAD	PHF23 →	+0.375	+2.735	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,356 associations by consensus.

MDH1 by CEMIP2 expression — STAD

Explore this box plot interactively →