CEMIP2

Across TCGA cell cohorts, CEMIP2 mutation is significantly associated with the RNA expression of many other genes, with 194 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEMIP2-associated genes across cancer lineages are TFAP2D, GALP, and OR5C1. Each is linked with CEMIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEMIP2-to-partner and partner-to-CEMIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFAP2D grouped by CEMIP2-low versus CEMIP2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEMIP2→partner) and Y-score (partner→CEMIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	TFAP2D →	+0.023	+4.807	<.001	.006	3	2
BLOOD_Lymphoma	GALP →	+0.010	+3.472	<.001	.002	3	2
BLOOD_Myeloma	OR5C1 →	+0.023	+4.807	<.001	.006	3	1
BLOOD_Myeloma	LALBA →	+0.030	+4.807	<.001	.006	3	1
LUNG_SCLC	OR11H1 →	+0.063	+4.459	<.001	.001	3	1
BLOOD_Leukemia	LRIT1 →	+0.037	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 194 associations by consensus.

TFAP2D by CEMIP2 expression — BLOOD_Myeloma

Explore this box plot interactively →