CELSR3

Across TCGA patient cohorts, CELSR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,933 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CELSR3-associated proteins across cancer lineages are SF3B3, RIF1, and GINS4. Each is linked with CELSR3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CELSR3-to-partner and partner-to-CELSR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CELSR3 versus SF3B3 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CELSR3→partner) and Y-score (partner→CELSR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.281	+1.130	<.001	<.001	3	6
LSCC	RIF1 →	+0.399	+0.591	<.001	.001	3	5
UCEC	GINS4 →	+0.724	+0.814	<.001	<.001	3	5
UCEC	AATF →	+0.352	+0.833	.001	<.001	3	5
GBM	HCFC1 →	+0.295	+1.025	<.001	<.001	3	5
LSCC	USP39 →	+0.293	+0.582	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,933 associations by consensus.

CELSR3 vs SF3B3 — GBM

Explore this scatter interactively →