CELSR2

Across TCGA patient cohorts, CELSR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,773 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CELSR2-associated proteins across cancer lineages are ADNP, MLKL, and NONO. Each is linked with CELSR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CELSR2-to-partner and partner-to-CELSR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CELSR2 versus ADNP in GBM, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CELSR2→partner) and Y-score (partner→CELSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADNP →	+0.376	+0.548	.001	.002	3	6
GBM	MLKL →	-0.383	-0.623	.004	<.001	3	5
GBM	NONO →	+0.158	+0.449	<.001	.009	3	5
BRCA	TXNDC5 →	-0.666	-1.552	<.001	<.001	3	5
BRCA	CTSS →	-0.636	-1.069	<.001	<.001	3	5
GBM	DOK2 →	-0.686	-0.671	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,773 associations by consensus.

CELSR2 vs ADNP — GBM

Explore this scatter interactively →