CELP

Across TCGA pan-cancer cohorts, CELP RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CELP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CELP RNA is repressed in tumor relative to normal tissue. In most cancer types CELP is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, COAD, and KIRC are the cancer types where CELP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CELP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	−0.078	<.001	11	view →
COAD	All	II,III,IV	+0.976	<.001	8	view →
KIRC	Male	All	−0.048	<.001	7	view →
HNSC	Male	III,IV	+0.064	.015	3	view →
READ	Female	All	+2.582	.001	2	view →
UCEC	All	All	+0.066	.036	2	view →
THCA	All	All	−0.013	.004	2	view →
CHOL	All	All	+0.068	.024	1	view →
HNSC	Female	IV	−0.026	.001	1	view →
LIHC	All	II,III,IV	+0.011	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 9 lineages.

CELP–KIRP

Open the KIRP breakdown →