CELF6

Across TCGA patient cohorts, CELF6 mutation is significantly associated with the RNA expression of many other genes, with 3,321 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CELF6-associated genes across cancer lineages are MIR6859-2, NMBR-AS1, and MIR100. Each is linked with CELF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF6-to-partner and partner-to-CELF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6859-2 grouped by CELF6-low versus CELF6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF6→partner) and Y-score (partner→CELF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6859-2 →	+0.275	+1.742	<.001	.009	3	2
SKCM	NMBR-AS1 →	+0.262	+4.513	<.001	.009	3	2
UCEC	MIR100 →	+0.131	+3.370	<.001	.002	3	2
UCEC	RNU6ATAC30P →	+0.321	+1.932	<.001	.001	3	2
STAD	MIR488 →	+0.300	+5.798	<.001	.003	3	2
UCEC	YTHDF3-AS1 →	+0.728	+3.839	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,321 associations by consensus.

MIR6859-2 by CELF6 expression — UCEC

Explore this box plot interactively →