CELF6

Across TCGA patient cohorts, CELF6 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CELF6-associated genes across cancer lineages are PRDX1, Rad50, and Bim. Each is linked with CELF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF6-to-partner and partner-to-CELF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRDX1 grouped by CELF6-low versus CELF6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF6→partner) and Y-score (partner→CELF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRDX1 →	+0.207	+2.000	.012	.030	3	2
UCEC	Rad50 →	-0.297	-2.415	.002	.003	3	2
UCEC	Bim →	-0.212	-1.906	.044	.016	3	2
UCEC	Caspase-7-cleavedD198 →	+0.963	+1.874	<.001	.049	3	2
UCEC	EGFR_pY1068 →	-0.259	-2.415	.010	.003	3	1
UCEC	eIF4E →	+0.221	+2.415	.009	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

PRDX1 by CELF6 expression — UCEC

Explore this box plot interactively →