CELF6

Across TCGA cell cohorts, CELF6 mutation is significantly associated with the mutation status of many other genes, with 748 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CELF6-associated genes across cancer lineages are IQCH, ILVBL, and ACVRL1. Each is linked with CELF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF6-to-partner and partner-to-CELF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCH grouped by CELF6-low versus CELF6-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF6→partner) and Y-score (partner→CELF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IQCH →	+4.415	+4.977	.007	.007	1	2
OVARY	ILVBL →	+4.415	+4.977	.007	.007	1	2
OVARY	ACVRL1 →	+4.415	+4.977	.007	.007	1	2
BLOOD_Lymphoma	TRIM9 →	+4.429	+5.247	.005	.005	1	2
LARGE_INTESTINE	FAM83D →	+4.087	+5.044	.001	.001	1	2
BLOOD_Lymphoma	FGF14 →	+5.014	+5.584	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 748 associations by consensus.

IQCH by CELF6 expression — OVARY

Explore this box plot interactively →