CELF3

Across TCGA cell cohorts, CELF3 mutation is significantly associated with the mutation status of many other genes, with 3,444 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CELF3-associated genes across cancer lineages are SLTM, COBLL1, and CR2. Each is linked with CELF3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CELF3-to-partner and partner-to-CELF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLTM grouped by CELF3-low versus CELF3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF3→partner) and Y-score (partner→CELF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLTM →	+4.479	+5.635	<.001	<.001	1	4
LARGE_INTESTINE	COBLL1 →	+1.932	+2.693	.004	.004	1	3
BREAST	CR2 →	+4.297	+4.857	.009	.009	1	3
BREAST	HOXB3 →	+4.297	+4.857	.009	.009	1	3
BREAST	ERGIC3 →	+5.297	+5.297	.004	.004	1	3
BREAST	VIL1 →	+4.297	+4.857	.009	.009	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,444 associations by consensus.

SLTM by CELF3 expression — BLOOD_Leukemia

Explore this box plot interactively →