CELF3

Across TCGA cell cohorts, CELF3 mutation is significantly associated with the drug of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CELF3-associated genes across cancer lineages are Niraparib, GSK690693, and 123138. Each is linked with CELF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF3-to-partner and partner-to-CELF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Niraparib grouped by CELF3-low versus CELF3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF3→partner) and Y-score (partner→CELF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Niraparib →	+0.362	+2.868	.031	.022	3	1
LARGE_INTESTINE	GSK690693 →	+0.667	+2.874	.004	.021	3	1
LARGE_INTESTINE	123138 →	+0.315	+2.871	.024	.021	2	1
LARGE_INTESTINE	GSK429286A →	+0.449	+2.874	.001	.021	2	1
LARGE_INTESTINE	LMB_AB1 →	+0.283	+2.871	.046	.021	1	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.470	+2.868	.047	.022	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Niraparib by CELF3 expression — LARGE_INTESTINE

Explore this box plot interactively →