CELF2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CELF2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CELF2-associated genes across cancer lineages are OR9K2, SCGB1C1, and GSG1L2. Each is linked with CELF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELF2-to-partner and partner-to-CELF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9K2 grouped by CELF2-low versus CELF2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELF2→partner) and Y-score (partner→CELF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR9K2 →+0.024+6.124<.001<.00132
BREASTSCGB1C1 →+0.074+5.169<.001.00531
LARGE_INTESTINEGSG1L2 →+0.013+4.022<.001.00631
BLOOD_LeukemiaCRYBB3 →+0.078+4.152.003.00931
BLOOD_LeukemiaZSWIM2 →+0.025+4.409.004.00531
BLOOD_LeukemiaKRT25 →+0.010+5.569<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR9K2 by CELF2 expression — BLOOD_Leukemia

Box plot of OR9K2 in CELF2-low vs CELF2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration