CELF2-AS2

Across TCGA pan-cancer cohorts, CELF2-AS2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated CELF2-AS2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CELF2-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CELF2-AS2 expression acts as an unfavorable survival marker.

LUSC, KIRP, and KIRC are the cancer types where CELF2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	II,III,IV	0.273	0.725	<.001	78	view →
KIRP	OS	Tertile	II,III,IV	0.111	0.769	<.001	63	view →
KIRC	DFS	Tertile	II,III,IV	0.166	0.768	<.001	36	view →
KICH	DFS	Tertile	III,IV	0.025	0.773	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
LIHC	OS	Tertile	All	0.089	0.783	<.001	36	view →
PCPG	DFS	Tertile	All	0.075	0.773	<.001	27	view →
OV	DFS	Median	IV	0.357	0.544	.008	18	view →
SARC	DFS	Tertile	All	0.319	0.532	.008	12	view →
STAD	DFS	Quartile	All	0.397	0.627	.011	10	view →
GBM	DFS	Tertile	All	0.115	0.316	.006	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

CELF2-AS2–LUSC (DFS)

Open the LUSC breakdown →