CELF2-AS1

Across TCGA pan-cancer cohorts, CELF2-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated CELF2-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CELF2-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CELF2-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, UVM, and READ are the cancer types where CELF2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.765	0.616	<.001	123	view →
UVM	DFS	Tertile	II,III,IV	0.271	0.739	<.001	103	view →
READ	OS	Quartile	All	0.876	0.285	<.001	40	view →
UCS	DFS	Median	III,IV	0.595	0.225	.001	24	view →
CHOL	DFS	Quartile	All	0.614	0.204	.022	22	view →
THCA	OS	Quartile	All	0.729	1.000	.008	14	view →
LAML	DFS	Median	All	0.506	0.283	.023	12	view →
BRCA	OS	Median	III,IV	0.940	0.862	.011	12	view →
COAD	DFS	Median	All	0.349	0.598	.011	11	view →
LUAD	OS	Tertile	II,III,IV	0.526	0.318	.018	9	view →
LIHC	OS	Quartile	II,III,IV	0.884	0.613	.013	7	view →
ESCA	OS	Median	III,IV	0.564	0.331	.033	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

CELF2-AS1–HNSC (DFS)

Open the HNSC breakdown →