CELF1

Across TCGA pan-cancer cohorts, CELF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CELF1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CELF1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CELF1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where CELF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.132	1.000	.010	36	view →
CCRCC	DFS	Tertile	All	0.821	0.973	.006	31	view →
LUAD	OS	Quartile	II,III,IV	0.299	0.588	.038	2	view →
LSCC	OS	Quartile	All	0.880	0.648	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CELF1–HNSC (OS)

Open the HNSC breakdown →