Across TCGA pan-cancer cohorts, CELA3B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CELA3B data layer compared with 19 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CELA3B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CELA3B expression acts as an unfavorable survival marker.

COAD, GBM, and LUSC are the cancer types where CELA3B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.054	0.871	<.001	24	view →
GBM	DFS	Median	All	0.066	0.257	.019	6	view →
LUSC	OS	Median	All	0.176	0.724	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: CELA3B tumor-vs-normal RNA expression · all CELA3B data types