CELA3B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CELA3B mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CELA3B-associated genes across cancer lineages are IQCF2, LCE1C, and ODF1. Each is linked with CELA3B in more than 1 cancer types. Because this analysis shows association rather than direction, both CELA3B-to-partner and partner-to-CELA3B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELA3B→partner) and Y-score (partner→CELA3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYIQCF2 →+0.052+5.196<.001.00531
OVARYLCE1C →+0.058+5.196<.001.00531
LUNG_NSCLC_LUADODF1 →+0.065+4.093<.001.00431
LUNG_NSCLC_LUADOR6C2 →+0.361+4.189<.001.00231
LUNG_NSCLC_LUADOR4C12 →+0.013+4.078<.001.00931
LUNG_NSCLC_LUADEXOC1L →+0.152+3.544<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration